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Available from these sellers. Nasal decongestant Levmetamfetamine 50mg Fast relief from nasal congestion. PillPack by Amazon Pharmacy. Have a question? There was a problem completing your request. Please try your search again later. Product details Shipping Weight: 0.
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Abuse potential in Vicks Nasal Inhalers (levmetamfetamine)?
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Verified Purchase. This comes pretty close though! Love these as much as the Vicks ones they used to sell. This is just like vicks inhalers works great. I like this product because it helps my nose from feeling stopped up.
One person found this helpful. Smells like menthol but has no use at all. If your nose is congested, you better use Afrin or such, because this thing is useless. See all reviews from the United States.Levomethamphetamine [note 1] is the levorotatory L- enantiomer form of methamphetamine. Levomethamphetamine is a sympathomimetic vasoconstrictor which is the active ingredient in some over-the-counter OTC nasal decongestant inhalers in the United States.
Levomethamphetamine crosses the blood-brain-barrier and acts as a TAAR1 agonist functioning as a selective norepinephrine releasing agent with few or no effects on the release of dopamineso it affects the central nervous systemalthough its effects are qualitatively distinct relative to those of dextromethamphetamine. Levomethamphetamine is the active metabolite of the antiparkinson's drug selegiline.
Selegiline itself has neuroprotective and neuro-rescuing effects, but concern over the resulting levomethamphetamine's neurotoxicity led to development of alternative MAO B inhibitors, such as rasagilinethat do not produce toxic metabolites.
When the nasal decongestant is taken in excess, levomethamphetamine has potential side effects resembling those of other sympathomimetic drugs ; these effects include hypertension elevated blood pressuretachycardia rapid heart ratenauseastomach crampsdizzinessheadachesweatingmuscle tensionand tremors. In a study of psychoactive effects of levomethamphetamine, the intravenous administration of 0.
The study did not test the oral administration of levomethamphetamine. Currently there are no studies demonstrating "drug liking" scores of oral levomethamphetamine that are similar to racemic methamphetamine or dextromethamphetamine in either recreational users or medicinal users. Levomethamphetamine can register on urine drug screens as either methamphetamine, amphetamine, or both, depending on the subject's metabolism and dosage.
L-methamphetamine metabolizes completely into L-amphetamine after a period of time. From Wikipedia, the free encyclopedia.
The Clinical Pharmacology of Intranasal l-Methamphetamine
IUPAC name. Interactive image. Main article: Selegiline. MAO B is an enzyme that metabolizes dopamine, the neurotransmitter deficient in Parkinson's Syndrome. United States Food and Drug Administration. April Archived from the original on 18 September Retrieved 7 March Topical nasal decongestants -- i For products containing levmetamfetamine identified in The product delivers in each milliliters of air 0.
Pubchem Compound. National Center for Biotechnology Information. Retrieved 2 January PubChem Compound. Archived from the original on 18 October Retrieved 17 October The Journal of Pharmacology and Experimental Therapeutics.
Clinical Pharmacology and Therapeutics. The Journal of Neuroscience. Archived from the original on 30 October Topical Nasal Decongestants Most topical nasal decongestants also carry the warning against unsupervised use with hypertension. This includes oxymetazoline e. When hypertensive patients request a nasal decongestant, the pharmacist can recommend several alternatives.
Propylhexedrine e. Another option is the nasal strip e. When properly applied, the strip can open the nostrils slightly, and perhaps sufficiently to allow the patient to breathe without use of a pharmacologically active ingredient. October Current Medicinal Chemistry.Douglas L. What you do to help people through this [A-Fib] process is really incredible.
Hugh G. I certainly recommend it for patients who want to know more about atrial fibrillation than what they will learn from doctors She loves it and finds it very useful to help her in dealing with atrial fibrillation. You managed to combine an encyclopedic compilation of information with the simplicity of presentation that enhances the delivery of the information to the reader.
This is not an easy thing to do, but you have been very, very successful at it. Steve Ryan, PhD, provides a comprehensive guide for persons seeking to find a cure for their Atrial Fibrillation. Last updated: March 14, As an A-Fib patient, did you notice these over-the-counter decongestants often contain a warning such as:.
When you have a stuffed up nose from a cold or allergies, a decongestant can cut down on the fluid in the lining of your nose. That relieves swollen nasal passages and congestion.
The Problem: When taking a decongestant, heart rate and blood pressure go up, the heart beats stronger, blood vessels constrict in nasal passages reducing fluid build-up. But not for patients with high blood pressure, heart disease or, specifically, Atrial Fibrillation.
Decongestants cause the blood vessels to shrink and blood pressure to rise. Perfect conditions that can trigger or induce an episode of their A-Fib. Check your Cold Medicine: The main active ingredient in many decongestants is pseudoephedrine, a stimulant. It is well known for shrinking swollen nasal mucous membranes. To find out if your cold medicine contains a decongestant, start by reading the label. Phenylephrine: a Safe Substitute? A substitute for pseudoephedrine is phenylephrine.
In general, phenylephrine is milder than pseudoephedrine but also less effective in treating nasal congestion. As with other decongestants, it causes the constriction of blood vessels and increases blood pressure. There is anecdotal evidence that products with the substitute phenylephrine might be less of a trigger for A-Fib than products with pseudoephedrine.
Lompocsue at yahoo. Antihistamines reduce the effects of histamine in the body which can produce sneezing, runny nose, etc. Though they can lessen your symptoms, some can aggravate a heart condition, or be dangerous when mixed with blood pressure drugs and certain heart medicines. Antihistamines can be dangerous when mixed with blood pressure drugs and certain heart medicines.
Heart-safe Antihistamines: Compared to decongestants, antihistamines are often better tolerated by people with A-Fib. Some heart-safe antihistamines that can help with a stuffy nose from a cold include:.Return Home Inxight: Drugs. Search Substances. Structure Search. Methamphetamine is a strong central nervous system CNS stimulant and is a sympathomimetic drug.
It is a scheduled drug in most countries due to its high potential for addiction and abuse. Methamphetamine enters the brain and triggers a cascading release of norepinephrine, dopamine and serotonin. To a lesser extent methamphetamine acts as a dopaminergic and adrenergic reuptake inhibitor and in high concentrations as a monamine oxidase inhibitor MAOI. The mechanism of action involved in producing the beneficial behavioral changes seen in hyperkinetic children receiving methamphetamine is unknown.
Methamphetamine has been identified as a potent full agonist of trace amine-associated receptor 1, and also, as an agonist of the alpha-2 adrenergic receptors.
Medications to Avoid if You Have High Blood Pressure
Methamphetamine increases extracellular dopamine in reward-relevant pathways by interacting at vesicular monoamine transporter-2 VMAT2 to inhibit dopamine uptake and promote dopamine release from synaptic vesicles, increasing cytosolic dopamine available for reverse transport by the dopamine transporter DAT.
CNS Activity. CNS Active. Dainippon Pharmaceutical.
Curator's Comment: methamphetamine, was developed in Japan in Approval Year. Synaptic vesicular amine transporter. Attention Deficit Disorder with Hyperactivity.
Trace amine-associated receptor 1. Adrenergic receptor alpha Monoamine transporter. Negative Allosteric Modulator. Approved Use Attention Deficit Disorder with Hyperactivity Methamphetamine hydrochloride tablets are indicated as an integral part of a total treatment program which typically includes other remedial measures psychological, educational, social for a stabilizing effect in children over 6 years of age with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: moderate to severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity.
The diagnosis of this syndrome should not be made with finality when these symptoms are only of comparatively recent origin. Nonlocalizing soft neurological signs, learning disability, and abnormal EEG may or may not be present, and a diagnosis of central nervous system dysfunction may or may not be warranted. Exogenous Obesity As a short-term i.
Hay Fever. Approved Use Attention Deficit Disorder with Hyperactivity: DESOXYN tablets are indicated as an integral part of a total treatment program which typically includes other remedial measures psychological, educational, social for a stabilizing effect in children over 6 years of age with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: moderate to severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity.
Exogenous Obesity: as a short-term i. Approved off-label. Title Date PubMed Brain mechanisms of hallucinogens and entactogens. Sample Use Guides. The product delivers in each ml of air 0. Levomethamphetamine were evaluated using 10 different concentrations run in duplicate.
The effect of test compound on internal calcium mobilization was determined with a FlexStation set for bottom read with nm excitation and nm emission wavelengths. Agonist Inhibitor Negative Allosteric Modulator Approved Synaptic vesicular amine transporter Adrenergic receptor alpha-2 Monoamine transporter Trace amine-associated receptor 1.
DESOXYN Approved Use Attention Deficit Disorder with Hyperactivity Methamphetamine hydrochloride tablets are indicated as an integral part of a total treatment program which typically includes other remedial measures psychological, educational, social for a stabilizing effect in children over 6 years of age with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: moderate to severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity.Levomethamphetamine which is the active ingredient used in some over-the-counter nasal decongestants such as inhalers.
Methamphetamine is a synthetic stimulant drug used for both medicinal and recreational purposes the latter use is illegal in most countries — see Legal issues. Like most stimulants, methamphetamine can cause a strong feeling of euphoria, thus creating the potential for addiction. Illicit methamphetamine comes in a variety of forms. Most commonly it is found as a colorless crystalline solid, sold on the street under a variety of names, such as: crystal meth or shards or crystal, glass, P, ice, chimichanga or Tina.
Colorful flavored pills containing methamphetamine and caffeine are known as yaba Thai for "crazy medicine".
See the list of street names for a more comprehensive list of common street names for methamphetamine. Methamphetamine found on the street may be pure, or adulterated with chemicals that were used to synthesize it. In some instances, it may be diluted or cut with non-psychoactive substances like inositol. In other instances, it may be mixed with other psychoactive drugs.
Methamphetamine was first synthesized in in Japan by the chemist A. The method of synthesis was reduction of ephedrine using red phosphorus and iodine. Methamphetamine is closely related to amphetamine, which was first synthesized in by Lazar Edeleanu, a Romanian chemist. Over time, the chemical's use, distribution, and place in society has changed from insignificant, to controversially beneficial, to infamous.
The Nazis widely distributed methamphetamine to their soldiers for use as a stimulant, particularly to SS personnel and Wehrmacht forces in the Eastern Front. Adolf Hitler received shots of methamphetamine from his personal physician, Theodore Morell.
After World War II, a massive supply of methamphetamine, formerly stockpiled by the Japanese military, became available in Japan under the street name shabu. The Japanese banned the drug soon after World War II, which is thought to have added to the growing yakuza activities related to illicit drug production. Today, the Japanese underworld is still associated with the drug, although its use is discouraged by strong social taboos.
With the s came a rise in the legal prescription of methamphetamine to the American public. According to the edition of Pharmacology and Therapeutics by Arthur Grollmanit was to be prescribed for "narcolepsy, post-encephalitic parkinsonism, alcoholism, The s saw the start of the significant use of clandestine manufacture to supply methamphetamine.
Prior toU. The recreational use of methamphetamine sky-rocketed in the s. Inthe U. In spite of this, its use expanded throughout the rural United States, especially in the Midwest and South. Growth of methamphetamine use continues into the 21st century, and many states are considering tougher legislation.
On August 8,an issue of Newsweek devoted a cover story to methamphetamine and its abuse, including criticism of the Bush administration's policies regarding methamphetamine. Newsweek blamed the administration for not devoting enough resources to education about and prevention of the drug's use. The Bush administration has countered with the position that cannabis is a dangerous 'gateway drug', so prevention of cannabis use will prevent potential abusers from trying and becoming hooked on "hard" drugs such as methamphetamine.
Meanwhile, the online magazine Slate posted an article in reaction to the Newsweek articleattacking Newsweek for failing to appropriately cite sources and data to back up the claim that this is a "new" problem. The topic remains controversial.FDA has not evaluated whether this product complies. If you are a consumer or patient please visit this version. Out of scope information includes radiopharmaceuticals, contrast media, herbals, homeopathics, and food.
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Levmetamfetamine 50 mg. Nasal decongestant. If swallowed, get medical help or contact a Poison Control Center right away. Distributed by C. Version Files Dec 20, 2 current download Mar 25, 1 download. NDC 1 Product Information. Inactive Ingredients. Marketing Information.Sinutab is a brand name of medicinal caplets owned by the pharmaceutical company, Pfizer 4. Sinutab products are manufactured for relieving sinus, nasal and chest symptoms caused by the common cold, local infections and allergies 4.
Sinutab Non-Drying caplets are used as a decongestant and expectorant combination, for symptoms caused by bronchitis and the common cold 2 4. The two active ingredients in Sinutab Non-Drying are guaifenesen and pseudoephedrine hydrochloride 2. Guaifenesin is classified as the expectorant and it helps loosen phlegm from the throat and chest, which makes coughing productive.
Pseudoephedrine is classified as the nasal decongestant and it helps to decrease swelling in the nasal passages and constrict blood vessels. Sinutab Non-Drying Maximum Strength contains mg of guaifenesin and 30 mg of pseudoephedrine per caplet 2.
The two active ingredients in Sinutab Sinus are acetaminophen and phenylephrine hydrochloride 4. Acetaminophen is classified as a pain and fever reducer, and works by affecting how the brain processes pain and regulates body temperature.
Phenylephrine is classified as the nasal decongestant and helps to shrink dilated blood vessels in the nasal passages. Sinutab Sinus Maximum Strength contains mg of acetaminophen and 5 mg of phenylephrine per caplet 4. The Extra Strength variety contains more acetaminophen mg.
Sinutab Sinus Allergy caplets are used to temporarily relieve symptoms of hay fever, runny nose, sinus congestion, sneezing, watery eyes, itchy nose or throat, and headache caused by allergies or the common cold 4. The three active ingredients in Sinutab Sinus Allergy are acetaminophen, pseudoephedrine hydrochloride and chlorpheniramine maleate 4. Acetaminophen works as an analgesic and psuedoephedrine as a nasal decongestant, as noted. Sinutab Sinus Allergy Maximum Strength contains mg of acetaminophen, 30 mg of pseudoephedrine and 2 mg of chlorpheniramine per caplet 4.
Sinutab is a brand name of medicinal caplets owned by the pharmaceutical company, Pfizer. The two active ingredients in Sinutab Sinus are acetaminophen and phenylephrine hydrochloride.
Sinutab Sinus Maximum Strength contains mg of acetaminophen and 5 mg of phenylephrine per caplet. Sinutab Sinus Allergy caplets are used to temporarily relieve symptoms of hay fever, runny nose, sinus congestion, sneezing, watery eyes, itchy nose or throat, and headache caused by allergies or the common cold.